CD28 antibody (FITC)

Catalog No. ABIN227415

Product Details anti-CD28 Antibody (FITC)

Target: CD28

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This CD28 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: CD28 is a cell surface glycoprotein expressed by a subset of T lymphocytes. The antigen is a disulphide-linked homodimer of 44kD chains. CD28 is a ligand for the B cell marker CD80 (B7) and is important in the interaction of B and T cells during the immune response. It has been reported that this clone also recognizes an epitope of CD28 expressed by NK cells, which is not recognized by clones of 9.3 or CD28.2 (1.).

Purification: Ion exchange chromatography

Immunogen: Human peripheral blood T-cells.

Type of Immunogen: Cells

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo

Usage: Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD28

Target: CD28

Alternative Name: CD28 (CD28 Products)

Synonyms: Tp44 antibody, CD28RNA antibody, cd28 antibody, CD28 molecule antibody, CD28 antigen antibody, Cd28 molecule antibody, CD28 molecule L homeolog antibody, CD28 antibody, Cd28 antibody, cd28.L antibody

Background: Name/Gene ID: CD28

Synonyms: CD28, CD28 antigen, CD28 antigen (Tp44), Tp44, CD28 Molecule

Gene ID: 940

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response