CD55 antibody
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- Target See all CD55 Antibodies
- CD55 (Complement Decay-Accelerating Factor (CD55))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD55 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificity
- Recognizes the CD55 antigen, a 70kD glycoprotein also known as Decay Accelerating Factor (DAF). Distributed on erythrocytes and other circulating blood cells and also on cells in non-hemopoietic tissue particularly epithelium and endothelium. Found specifically at the fetal-maternal interfaces in placenta. CD55 has reduced expression on individuals with paroxysmal nocturnal hemoglobinuria. Has a functional binding affinity to erythrocytes of 8.7 x 107 M-1. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. Recognizes the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF.
- Purification
- Protein G purified
- Immunogen
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Human fibroblast cell line.
Type of Immunogen: Cells - Isotype
- IgG1
- Top Product
- Discover our top product CD55 Primary Antibody
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- Application Notes
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Approved: Flo, IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL Method sheets are available on request. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
- deionized water
- Concentration
- Lot specific
- Buffer
- 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Alternative Name
- CD55 (CD55 Products)
- Background
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Name/Gene ID: CD55
Synonyms: CD55, CD55 antigen, Decay-accelerating factor, TC, CR, CROM, DAF - Gene ID
- 1604
- UniProt
- P08174
- Pathways
- Complement System, Regulation of Leukocyte Mediated Immunity
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