CD226 antibody (Biotin)

Catalog No. ABIN209063

Product Details anti-CD226 Antibody (Biotin)

Target: CD226

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD226 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Recognizes human CD226. Reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

Purification: Protein G purified

Immunogen: Human cytotoxic T lymphocyte clone.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, IP

Usage: Suitable for use in Flow Cytometry and Immunoprecipitation. Flow Cytometry: Neat 1:10. Use 10 μL of the suggested working dilution to label 1x1 x10⁶ in 100 μL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 1.0 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD226

Target: CD226

Alternative Name: DNAM-1 / CD226 (CD226 Products)

Background: Name/Gene ID: CD226

Synonyms: CD226, Adhesion glycoprotein, CD226 Molecule, CD226 antigen, DNAM-1, DNAM1, DNAX accessory molecule-1, TLiSA1, PTA1, DNAX accessory molecule 1

Gene ID: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints