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CD11b antibody

ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 unconjugated

Catalog No. ABIN206892

Datasheet as PDF

Target See all CD11b (ITGAM) Antibodies

CD11b (ITGAM) (Integrin alpha M (ITGAM))
Reactivity
253

166

66

34

20

19

17

14

11

10

7

4

4

2

2

1
Human
Host
139

105

105

2

1

1
Mouse
Compatible Secondaries
Clonality
255

94

2
Monoclonal
Conjugate
119

39

30

27

20

9

7

7

5

5

5

5

4

4

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This CD11b antibody is un-conjugated
Application
265

83

80

78

60

45

36

24

23

19

14

14

7

6

5

5

4

4

3

2

2

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity

Recognizes CD11b antigen (Mac-1), a 165 kD type 1 transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells. The CD11b mediates neutrophil and monocyte interactions with stimulated endothelium.

Purification

Protein A purified

Immunogen

Human granulocytes.

Type of Immunogen: Cells

Clone

MEM-174

Isotype

IgG2a

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ITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated

anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 77-180) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 31-160) antibody
ITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) antibody (FITC)
ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC

anti-Integrin alpha M (ITGAM) antibody (Biotin)
ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin

anti-Integrin alpha M (ITGAM) antibody (PE)
ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE

anti-Integrin alpha M (ITGAM) (AA 623-728) antibody
ITGAM Reactivity: Human ELISA, ICC Host: Mouse Monoclonal 3A10H5 unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3340 unconjugated

Application Notes

Approved: Flo, IP

Usage: Flow Cytometry: Recommended dilution - 1 μg/mL. Positive control - Peripheral Blood Lymphocytes. Immunoprecipitation: Positive control - Granulocytes. CD11b/CD18 transfectants. Application note - Immunoprecipitation with the antibody MEM-174 was successfu The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Not recommended for: IHC-P

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Azide free PBS, preserved by filter sterilization, approx,  pH 7.4.

Preservative

Azide free

Handling Advice

avoid freeze thaw cycles.

Storage

4 °C,-20 °C

Storage Comment

Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name

ITGAM / CD11b (ITGAM Products)

Background

Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gene ID

3684

UniProt

P11215

Pathways

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation