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CD4 antibody

CD4 Reactivity: Human FACS, IP, Func, BR, Neut, Inhibition Host: Mouse Monoclonal MEM-115 unconjugated

Catalog No. ABIN206889

Datasheet as PDF

Target See all CD4 Antibodies

CD4
Reactivity
335

209

121

48

24

20

19

18

17

10

10

10

10

10

10

9

9

9

8

5

4

2

1

1

1

1

1
Human
Host
352

147

113

3

3

1
Mouse
Compatible Secondaries
Clonality
473

138

5
Monoclonal
Conjugate
204

69

62

44

35

12

11

10

9

9

9

9

8

8

7

5

5

4

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
This CD4 antibody is un-conjugated
Application
497

191

127

101

93

69

69

42

39

34

31

28

10

8

7

7

6

6

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut), Blocking Antibody (Inhibition)

Specificity

Recognizes an epitope in the D1 domain of CD4 antigen, a 55 kD transmembrane glycoprotein expressed on a subset of T lymphocytes (helper T cells) and also on monocytes, tissue macrophages and granulocytes. It is negative in Western blotting even with non-reduced samples of cell lysates.

Purification

Protein A purified

Immunogen

Human thymocytes and T lymphocytes.

Type of Immunogen: Cells

Clone

MEM-115

Isotype

IgG2a

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CD4 Reactivity: Human, Mouse, Rat, Chicken, Pig FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 Reactivity: Human, Mouse, Rat, Chicken, Monkey, Dog, Pig, Cat, Cow, Rabbit, Sheep, Guinea Pig, Goat, Horse, Avian, Donkey, Hamster WB Host: Goat Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
CD4 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody
CD4 Reactivity: Human FACS, WB, CyTOF Host: Mouse Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) antibody
CD4 Reactivity: Mouse FACS, IP, IHC (fro), ICC, Func Host: Rat Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (AA 301-400) antibody
CD4 Reactivity: Human, Mouse, Rat FACS, WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 Reactivity: Human FACS Host: Mouse Monoclonal MEM-241 FITC

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 Reactivity: Human FACS Host: Mouse Monoclonal MEM-241 PE

anti-CD4 (CD4) antibody (PE)
CD4 Reactivity: Rat FACS Host: Mouse Monoclonal OX-35 PE

anti-CD4 (CD4) (AA 26-200) antibody
CD4 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Approved: Block, Flo, Func, Inhb, IP, Neut

Usage: Immunoprecipitation: excellent. Functional Application: The antibody MEM-115 blocks binding of HIV gp120 to CD4 Molecule and it also strongly inhibits CD4-MHC Class II interactions. Flow Cytometry: Recommended dilution - 3 μg/mL. Application notes:. Altho The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Not recommended for: IHC-P

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Azide free PBS, preserved by filter sterilization, approx,  pH 7.4.

Preservative

Azide free

Handling Advice

avoid freeze thaw cycles.

Storage

4 °C,-20 °C

Storage Comment

Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Target

CD4

Alternative Name

CD4 (CD4 Products)

Background

Name/Gene ID: CD4

Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule

Gene ID

920

UniProt

P01730

Pathways

TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events