CD11b antibody
-
- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
Reactivity
- Human, Baboon, Rhesus Monkey, Cynomolgus
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CD11b antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Recognizes the human CD11b cell surface glycoprotein, a 165kD molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes. Blocks some functions of CD11b, although full definition is still to be completed.
- No Cross-Reactivity
- Cat (Feline)
- Purification
- Protein G purified
- Immunogen
-
Rheumatoid synovial cells and human monocytes.
Type of Immunogen: Cells - Isotype
- IgG1
- Top Product
- Discover our top product ITGAM Primary Antibody
-
anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 145-340) antibodyITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE
anti-Integrin alpha M (ITGAM) (AA 623-728) antibodyITGAM Reactivity: Human ELISA, ICC Host: Mouse Monoclonal 3A10H5 unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3340 unconjugated
-
- Application Notes
-
Approved: Flo (1:10 - 1:100), IHC, IHC-Fr (1:100 - 1:1000), IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended. - Comment
-
Target Species of Antibody: Human
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing. Store undiluted.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
-
- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- ITGAM / CD11b (ITGAM Products)
- Background
-
Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain - Gene ID
- 3684
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
-
