CD16 antibody (Biotin)

Catalog No. ABIN206061

Product Details anti-CD16 Antibody (Biotin)

Target: CD16

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Specificity: Recognizes CD16, a 50-65 kD cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Has been reported to block the binding of IgG to the CD16 Molecule.

Purification: Ion exchange chromatography

Immunogen: Normal human peripheral blood granulocytes.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1 - 1:5)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL human whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD16

Target: CD16

Alternative Name: CD16 (CD16 Products)

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process