TNFRSF1A antibody

Catalog No. ABIN204876

Product Details anti-TNFRSF1A Antibody

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF1A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytotoxicity Test (CyTox)

Specificity: Recognizes the 60kD TNF-receptor on human cells as well as its soluble fragment and completely neutralizes the whole range of TNF effects.

Purification: Purified

Immunogen: Tumor Necrosis Factor Receptor.

Clone: 4-12

Isotype: IgG2a

Application Details

Application Notes: Approved: Ctox, Flo, IHC, IHC-Fr

Usage: Suitable for use in Flow Cytometry, Immunohistochemistry, neutralizes TNF-induced cytotoxicity on 4937 MCF-7, HeLA, and L929 cells, TNF-induced MHC expression is inhibited on K562 and Colo 205 cells, TNF induced IL-2R expression is inhibited on Yt cells. Immunohistochemistry: 1:150 (cryostat sections).

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, stabilizer and a preservative

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TNFRSF1A

Target: TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A))

Alternative Name: TNFRSF1A / TNFR1 (TNFRSF1A Products)

Background: Name/Gene ID: TNFRSF1A
Family: TNF Receptor

Synonyms: TNFRSF1A, CD120a, CD120a antigen, MS5, p60, TBP1, TNF-R55, TNFAR, TNFR1, p55-R, TNF-R, TNF-R-I, TNF-R1, TNF-RI, Tnfr, TNFR-I, TNFR1-d2, TNFR60, FPF, p55, Tbpi, TNFR55

Gene ID: 7132

UniProt: P19438

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C, Ubiquitin Proteasome Pathway