PRKDC antibody (AA 2607-2611)
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- Target See all PRKDC Antibodies
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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Binding Specificity
- AA 2607-2611
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRKDC antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects endogenous levels of total DNA PKcs protein.
- Purification
- Immunoaffinity Chromatography using epitope-specific peptide.
- Immunogen
- Peptide sequence around amino acids 2607~2611 (V-E-T-Q-A) derived from Human DNA PK.
- Top Product
- Discover our top product PRKDC Primary Antibody
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anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibody
PRKDC Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 3H6 unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4019-4128) antibodyPRKDC Reactivity: Human ELISA, WB, IF, IHC (p) Host: Mouse Monoclonal 1B9 unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) antibodyPRKDC Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC Reactivity: Human, Mouse ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 3899-4128) antibodyPRKDC Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 151-300) antibodyPRKDC Reactivity: Human, Rat ELISA, WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (C-Term) antibodyPRKDC Reactivity: Human, Mouse ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (pThr2647) antibodyPRKDC Reactivity: Human ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (AA 4075-4104), (C-Term) antibodyPRKDC Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB3465-3466 unconjugated
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- Application Notes
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Suitable for use in in Western blot (1: 500-1: 1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Target
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
- Alternative Name
- DNA-PKcs / PRKDC / XRCC7 (PRKDC Products)
- Background
- DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.Synonyms: DNA-dependent protein kinase catalytic subunit, DNPK1, HYRC, HYRC1, p460
- Gene ID
- 5591
- NCBI Accession
- NP_001075109
- UniProt
- P78527
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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