ICAM-3/CD50 antibody

Catalog No. ABIN1967144

Product Details anti-ICAM-3/CD50 Antibody

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM-3/CD50 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut)

Specificity: Monoclonal antibody MEM-04 reacts with CD50 (ICAM-3), a 120-130 kD type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells, it is negative on platelets and erythrocytes. The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).

Purification: Protein A purified

Sterility: Sterile filtered

Immunogen: Leukocytes of a patient suffering from LGL-type leukemia.

Type of Immunogen: Cells

Clone: MEM-04

Isotype: IgG1

Application Details

Application Notes: Approved: Block, Flo, Func, IHC, IHC-P, Neut

Usage: Flow Cytometry: Recommended dilution - 5 μg/mL. Immunohistochemistry (paraffin sections): Recommended dilution - 10 μg/mL. Positive tissue - tonsil. Functional Application: The antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, sterile filtered.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Alternative Name: ICAM3 / CD50 (ICAM3 Products)

Background: Name/Gene ID: ICAM3
Family: ICAM

Synonyms: ICAM3, CD50, CDW50, ICAM-R, CD50 antigen, ICAM-3

Gene ID: 3385