UCHL5 antibody

Catalog No. ABIN1882286

Product Details anti-UCHL5 Antibody

Target: UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UCHL5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged UCH37 protein was used to produced this monoclonal antibody.

Clone: 854CT5-5-6

Isotype: IgG1

Application Details

Application Notes: WB: 1:2000-1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-UCHL5 antibody (ABIN1882286)

Yao, Song, Xu, DeMartino, Florens, Swanson, Washburn, Conaway, Conaway, Cohen: "Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1." in: Nature cell biology, Vol. 8, Issue 9, pp. 994-1002, (2006) (PubMed).

Target Details for UCHL5

Target: UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))

Alternative Name: UCH37 (UCHL5) (UCHL5 Products)

Background: Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex, however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.

Molecular Weight: 37607

NCBI Accession: NP_001186190, NP_001186191, NP_001186192, NP_057068

UniProt: Q9Y5K5