Syndecan 1 antibody
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- Target See all Syndecan 1 (SDC1) Antibodies
- Syndecan 1 (SDC1)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Syndecan 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogen
- This CD138 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human CD138.
- Clone
- 480CT5-4-3
- Isotype
- IgG1
- Top Product
- Discover our top product SDC1 Primary Antibody
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- Application Notes
- IF: 1:10~50. WB: 1:100~500. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- Syndecan 1 (SDC1)
- Alternative Name
- CD138 (SDC1 Products)
- Background
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The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
- Molecular Weight
- 32462
- NCBI Accession
- NP_001006947, NP_002988
- UniProt
- P18827
- Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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