BAIAP2 antibody

Catalog No. ABIN1882211

Product Details anti-BAIAP2 Antibody

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAIAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged BAIAP2 protein was used to produced this monoclonal antibody.

Clone: 1037CT15-1-3

Isotype: IgG2b

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-BAIAP2 antibody (ABIN1882211)

Miyahara, Okamura-Oho, Miyashita, Hoshika, Yamada: "Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein." in: Journal of human genetics, Vol. 48, Issue 8, pp. 410-4, (2003) (PubMed).

Oda, Shiratsuchi, Nishimori, Inazawa, Yoshikawa, Taketani, Nakamura, Tokino: "Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1." in: Cytogenetics and cell genetics, Vol. 84, Issue 1-2, pp. 75-82, (1999) (PubMed).

Okamura-Oho, Miyashita, Ohmi, Yamada: "Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate." in: Human molecular genetics, Vol. 8, Issue 6, pp. 947-57, (1999) (PubMed).

Target Details for BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Alternative Name: BAIAP2 (BAIAP2 Products)

Background: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.

Molecular Weight: 60868

NCBI Accession: NP_001138360, NP_006331, NP_059344, NP_059345

UniProt: Q9UQB8