SF3A2 antibody (AA 166-194)

Catalog No. ABIN1881795

Product Details anti-SF3A2 Antibody

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Binding Specificity: AA 166-194

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SF3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human SF3A2.

Clone: RB42212

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SF3A2 antibody (ABIN1881795)

Tanackovic, Krämer: "Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo." in: Molecular biology of the cell, Vol. 16, Issue 3, pp. 1366-77, (2005) (PubMed).

Takenaka, Nakagawa, Miyamoto, Miki: "The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein." in: The Biochemical journal, Vol. 382, Issue Pt 1, pp. 223-30, (2004) (PubMed).

Target Details for SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Alternative Name: SF3A2 (SF3A2 Products)

Background: This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Molecular Weight: 49256

NCBI Accession: NP_009096

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization