SDHA antibody (C-Term)

Catalog No. ABIN1881780

Product Details anti-SDHA Antibody

Target: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Binding Specificity: AA 577-605, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: X, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-605 amino acids from the C-terminal region of human SDHA.

Clone: RB42344

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SDHA antibody (ABIN1881780)

Parfait, Chretien, Rötig, Marsac, Munnich, Rustin: "Compound heterozygous mutations in the flavoprotein gene of the respiratory chain complex II in a patient with Leigh syndrome." in: Human genetics, Vol. 106, Issue 2, pp. 236-43, (2000) (PubMed).

Hirawake, Wang, Kuramochi, Kojima, Kita: "Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the flavoprotein (Fp) subunit of liver mitochondria." in: Journal of biochemistry, Vol. 116, Issue 1, pp. 221-7, (1995) (PubMed).

Morris, Farnsworth, Ackrell, Turnbull, Birch-Machin: "The cDNA sequence of the flavoprotein subunit of human heart succinate dehydrogenase." in: Biochimica et biophysica acta, Vol. 1185, Issue 1, pp. 125-8, (1994) (PubMed).

Target Details for SDHA

Target: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Alternative Name: SDHA (SDHA Products)

Background: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.

Molecular Weight: 72692

NCBI Accession: NP_004159

UniProt: P31040