IFITM1 antibody (AA 37-66)

Catalog No. ABIN1881445

Product Details anti-IFITM1 Antibody

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Binding Specificity: AA 37-66

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IFITM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human IFITM1.

Clone: RB40554

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-IFITM1 antibody (ABIN1881445)

Ma, Zhang, Fu, Xia, Zhan, Li, Wang, Wu: "Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).

Mosbruger, Duggal, Goedert, Kirk, Hoots, Tobler, Busch, Peters, Rosen, Thomas, Thio: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, (2010) (PubMed).

Yang, Chen, Lin, Yu, Liu, Wang, Liu, Chen et al.: "Nickel catalysts bearing bidentate alpha-aminoaldimines for ethylene polymerization--independent and cooperative structure/reactivity relationship resulting from unsymmetric square planar..." in: Dalton transactions (Cambridge, England : 2003), Issue 7, pp. 1243-50, (2009) (PubMed).

Target Details for IFITM1

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Alternative Name: IFITM1 (IFITM1 Products)

Background: IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Molecular Weight: 13964

NCBI Accession: NP_003632

UniProt: P13164