CCT7 antibody (N-Term)

Catalog No. ABIN1881183

Product Details anti-CCT7 Antibody

Target: CCT7 (Chaperonin Containing TCP1, Subunit 7 (Eta) (CCT7))

Binding Specificity: AA 64-92, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT7 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, C, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human CCT7.

Clone: RB42785

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CCT7 antibody (ABIN1881183)

Mukherjee, Conway de Macario, Macario, Brocchieri: "Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes." in: BMC evolutionary biology, Vol. 10, pp. 64, (2010) (PubMed).

Zebol, Hewitt, Moretti, Lynn, Lake, Li, Vadas, Wattenberg, Pitson: "The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1." in: The international journal of biochemistry & cell biology, Vol. 41, Issue 4, pp. 822-7, (2009) (PubMed).

Guo, Han, Adam, Colburn, Wang, Dong, Eizirik, She, Wang: "Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress." in: Biochemical and biophysical research communications, Vol. 337, Issue 4, pp. 1308-18, (2005) (PubMed).

Hanafy, Martin, Murad: "CCTeta, a novel soluble guanylyl cyclase-interacting protein." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46946-53, (2004) (PubMed).

Imai, Soda, Murakami, Shoji, Abe, Takahashi: "A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 51901-10, (2003) (PubMed).

Target Details for CCT7

Target: CCT7 (Chaperonin Containing TCP1, Subunit 7 (Eta) (CCT7))

Alternative Name: CCT7 (CCT7 Products)

Background: This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

Molecular Weight: 59367

NCBI Accession: NP_001009570, NP_001159756, NP_001159757, NP_006420

UniProt: Q99832