E2F1 antibody (AA 69-223)
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- Target See all E2F1 Antibodies
- E2F1 (E2F Transcription Factor 1 (E2F1))
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Binding Specificity
- AA 69-223
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This E2F1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human E2F1 (AA: 69-223) expressed in E. Coli.
- Isotype
- IgG1
- Top Product
- Discover our top product E2F1 Primary Antibody
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anti-E2F Transcription Factor 1 (E2F1) (AA 69-223) antibody
E2F1 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 8G9 unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 Reactivity: Human WB, ELISA, IHC, FACS, IF Host: Rabbit Monoclonal 1D12 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 1 (E2F1) (AA 348-437) antibodyE2F1 Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 2E10 unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 133-362) antibodyE2F1 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 101-180) antibodyE2F1 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), FACS, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibodyE2F1 Reactivity: Human WB Host: Rabbit Polyclonal RB7913 unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 Reactivity: Human WB, IP, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibodyE2F1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibodyE2F1 Reactivity: Human WB, ELISA, IF (cc), IF (p), FACS, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pThr433) antibodyE2F1 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- Target
- E2F1 (E2F Transcription Factor 1 (E2F1))
- Alternative Name
- E2F1 (E2F1 Products)
- Background
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
- Molecular Weight
- 46.9 kDa
- Gene ID
- 1869
- UniProt
- Q01094
- Pathways
- p53 Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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