Dynactin 4 antibody (AA 57-298)

Catalog No. ABIN1843394

Product Details anti-Dynactin 4 Antibody

Target: Dynactin 4 (DCTN4)

Binding Specificity: AA 57-298

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Dynactin 4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Dynactin 4

Target: Dynactin 4 (DCTN4)

Alternative Name: DCTN4 (DCTN4 Products)

Background: Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping.Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.

Molecular Weight: 52.3 kDa

Gene ID: 51164

UniProt: Q9UJW0