TEAD1 antibody (N-Term)

Catalog No. ABIN184329

Product Details anti-TEAD1 Antibody

Target: TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEAD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MEPSSWSGSE SPAENMERMS DSADKPIDND AEGVWSPDIE QSFQEALAIY

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TEAD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TEAD1

Application Details

Application Notes: WB Suggested Anti-TEAD1 Antibody Titration: 2.5 µg/mL
Positive Control: Human Muscle.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 411 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TEAD1

Target: TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))

Alternative Name: TEAD1 / TEF1 / TCF13 (TEAD1 Products)

Background: TEAD1 is a transcriptional enhancer. It interacts with a muscle-specific cofactor to promote skeletal muscle gene expression. The mutation in the TEAD1 gene is the cause of Sveinsson's chorioretinal atrophy
Alias Symbols: AA, REF1, TCF13, TEF-1, NTEF-1, TCF-13, TEAD-1
Protein Interaction Partner: UBTD1, YAP1, GCAT, UBC, INSR, HLA-DMB, SOX2, VGLL2, VGLL4, VGLL1, MEF2C, MEF2B, MEF2A, SRF, TBP, TEAD1, MYH7, MAX, NCOA1,
Protein Size: 411

Molecular Weight: 46 kDa

Gene ID: 7003

NCBI Accession: NM_021961, NP_068780

UniProt: P28347

Pathways: Regulation of Lipid Metabolism by PPARalpha