CHRND antibody (N-Term)

Catalog No. ABIN184224

Product Details anti-CHRND Antibody

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Binding Specificity: N-Term

Reactivity: Human, Rat, Dog, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRND antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LTLGLLAALA VCGSWGLNEE ERLIRHLFQE KGYNKELRPV AHKEESVDVA

Predicted Reactivity: Cow: 91%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Pig: 100%, Rabbit: 86%, Rat: 85%, Zebrafish: 78%

Characteristics: This is a rabbit polyclonal antibody against CHRND. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRND

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 517 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRND

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Alternative Name: CHRND (CHRND Products)

Background: The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Alias Symbols: ACHRD, CMS2A, FCCMS, SCCMS
Protein Interaction Partner: GRB2, CHRNA1,
Protein Size: 517

Molecular Weight: 59 kDa

Gene ID: 1144

NCBI Accession: NM_000751, NP_000742

UniProt: Q07001