RNASEL antibody (C-Term)
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- Target See all RNASEL Antibodies
- RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
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Binding Specificity
- C-Term
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Reactivity
- Human, Pig, Cow, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RNASEL antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MKLKIGDPSL YFQKTFPDLV IYVYTKLQNT EYRKHFPQTH SPNKPQCDGA
- Predicted Reactivity
- Cow: 78%, Dog: 92%, Horse: 100%, Human: 100%, Pig: 92%
- Characteristics
- This is a rabbit polyclonal antibody against RNASEL. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNASEL
- Top Product
- Discover our top product RNASEL Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 741 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
- Alternative Name
- RNASEL (RNASEL Products)
- Background
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This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.
Alias Symbols: RNS4, PRCA1
Protein Interaction Partner: TCF12, UBC, ABCE1, AR, GSPT1,
Protein Size: 741 - Molecular Weight
- 84 kDa
- Gene ID
- 6041
- NCBI Accession
- NM_021133, NP_066956
- UniProt
- Q05823
- Pathways
- Hepatitis C
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