PRPF3 antibody (N-Term)

Catalog No. ABIN183978

Product Details anti-PRPF3 Antibody

Target: PRPF3 (PRP3 Pre-mRNA Processing Factor 3 Homolog (PRPF3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VDKLFEAVEE GRSSRHSKSS SDRSRKRELK EVFGDDSEIS KESSGVKKRR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRPF3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 683 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRPF3

Target: PRPF3 (PRP3 Pre-mRNA Processing Factor 3 Homolog (PRPF3))

Alternative Name: PRPF3 (PRPF3 Products)

Background: The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.[supplied by OMIM].
Alias Symbols: PRP3, RP18, HPRP3, Prp3p, HPRP3P
Protein Interaction Partner: FAM9B, TRIM39, SART3, CEP250, AURKB, UBC, TUBG1, LIN28A, MEPCE, WWOX, WBP4, TARDBP, MMS19, FRA10AC1, SNIP1, NKAP, CTNNBL1, ZCCHC10, U2AF2, SF3B2, SLU7, SMNDC1, RBM39, PRPF3, PCBP1, MFAP1, PATL1, RBM25, NOP58, LSM1, PABPC1, PRPF6, NNT, SRRM2, SUPT16H, SF3A
Protein Size: 683

Molecular Weight: 75 kDa

Gene ID: 9129

NCBI Accession: NM_004698, NP_004689

UniProt: O43395