EIF4G3 antibody (N-Term)

Catalog No. ABIN183966

Product Details anti-EIF4G3 Antibody

Target: EIF4G3 (Eukaryotic Translation Initiation Factor 4 gamma 3 (EIF4G3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4G3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TAASDQKQEE KPKPDPVLKS PSPVLRLVLS GEKKEQEGQT SETTAIVSIA

Predicted Reactivity: Cow: 85%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EIF4G3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4G3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 515 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF4G3

Target: EIF4G3 (Eukaryotic Translation Initiation Factor 4 gamma 3 (EIF4G3))

Alternative Name: EIF4G3 (EIF4G3 Products)

Background: EIF4G3 is probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. It is thought to be a functional homolog of EIF4G1.
Alias Symbols: eIF4G 3, eIF4GII, eIF-4G 3
Protein Interaction Partner: UBC, LGR4, TARDBP, ESR1, LIG4, EIF4G2, EIF4G1, EIF4A2, EIF4A1, SIRT7, VAV2, MKNK1, USP10, EIF3H, EIF3F, CAMK1, PABPC1, EIF4E,
Protein Size: 515

Molecular Weight: 57 kDa

Gene ID: 8672

NCBI Accession: NM_001198801