C5AR1 antibody

Catalog No. ABIN1838110

Product Details anti-C5AR1 Antibody

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C5AR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

Specificity: Recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone S5/1 was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31) and has recently been shown to recognize the heptameric peptide (D15DKDTLD21). Clone S5/1 has been shown to inhibit the binding of C5a to its receptor. Cross reacts with human.

Purification: Purified

Immunogen: C5aR Aâ,â€oe peptide: Met1 Aâ,â€oe Asn31.

Type of Immunogen: Synthetic peptide

Clone: S5-1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: C5AR1 / CD88 / C5a Receptor (C5AR1 Products)

Background: Name/Gene ID: C5AR1
Subfamily: Anaphylatoxin
Family: GPCR

Synonyms: C5AR1, C5A, C5a-R, C5a ligand, C5a receptor, CD88, C5a anaphylatoxin receptor, C5AR, C5R1, CD88 antigen

Gene ID: 728

UniProt: P21730

Pathways: Complement System