CBX8 antibody (C-Term)

Catalog No. ABIN183796

Product Details anti-CBX8 Antibody

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ARILGDPEEE SWSPSLTNLE KVVVTDVTSN FLTVTIKESN TDQGFFKEKR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against CBX8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CBX8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 389 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8 (CBX8 Products)

Background: CBX8 is one of the proteins homolog to the Polycomb group (PcG) proteins. They assemble to form large multiprotein complexes involved in gene silencing. Evidence suggests that PcG complexes are heterogeneous with respect to both protein composition and specific function.
Alias Symbols: PC3, RC1
Protein Interaction Partner: CCDC57, KRT40, FSD2, GPRASP2, LZTS2, TSGA10, HMBOX1, CCDC136, RPGRIP1, KCTD9, MTUS2, MID2, PNMA2, IKZF1, CALCOCO2, ZBTB14, TRAF2, TFCP2, SOX5, RING1, KIFC3, GOLGA2, PHC2, UBC, EED, RNF2, BMI1, SUZ12, MLLT1, LOC100131689, ZNF717, CHAMP1, HIST1H2BA, UBR1, E
Protein Size: 389

Molecular Weight: 43 kDa

Gene ID: 57332

NCBI Accession: NM_020649, NP_065700

UniProt: Q9HC52