TANK antibody (C-Term)

Catalog No. ABIN183653

Product Details anti-TANK Antibody

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Binding Specificity: C-Term

Reactivity: Human, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TANK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH

Predicted Reactivity: Human: 100%, Rabbit: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against TANK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TANK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 425 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TANK

Target: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Alternative Name: TANK (TANK Products)

Background: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, ther
Alias Symbols: TRAF2, I-TRAF
Protein Interaction Partner: CEP63, TP53BP2, SRSF11, UBC, TBK1, BIRC3, BIRC2, INPP5K, ATP6V1H, RACGAP1, TANK, IKBKE, IKBKG, AIMP2, TRAF2, TRAF1, SDC4, PLK1, SMAD3, LAMC1, KPNA2, HLA-C, FBLN1, COPB1, BIK, APP, TRAF3, TAB2, MAP3K14, HERC2, CD40, CBLB, TICAM1, APBA3, MARCH5, ZC3H12A, MA
Protein Size: 425

Molecular Weight: 48 kDa

Gene ID: 10010

NCBI Accession: NM_004180, NP_004171

UniProt: Q92844

Pathways: p53 Signaling, TLR Signaling, Activation of Innate immune Response