DHX16 antibody (N-Term)

Catalog No. ABIN183550

Product Details anti-DHX16 Antibody

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Horse, Goat, Rat, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX16 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KYQLVLEEEE TIEFVRATQL QGDEEPSAPP TSTQAQQKES IQAVRRSLPV

Predicted Reactivity: Cow: 86%, Goat: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 85%, Rabbit: 77%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against DHX16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1041 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DHX16

Target: DHX16 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 16 (DHX16))

Alternative Name: DHX16 (DHX16 Products)

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.
Alias Symbols: DBP2, PRP8, Prp2, DDX16, PRPF2, PRO2014
Protein Interaction Partner: NUDCD1, UBC, GPKOW, SF3B2, DHX38, DGCR14, CSNK2A1, XAB2, HELQ, PYROXD1, NAA40, LSM2, MIF4GD, GON4L, WDR44, EHD2, LSM5, LSM6, GCC2, TCEA2, MTR, GSPT1, GABPB1, APP, COIL, SNRNP27, SNRNP40, SIRT7, MEGF10, Bud13, TADA2A, SRRM2, SRRM1,
Protein Size: 1041

Molecular Weight: 115 kDa

Gene ID: 8449

NCBI Accession: NM_003587, NP_003578

UniProt: O60231