NFAT5 antibody (Middle Region)

Catalog No. ABIN183505

Product Details anti-NFAT5 Antibody

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Horse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFAT5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TIQTQDISQP GTFPAVSAAS QLPSSDALLQ QATQFQTREA QSRDTIQSDT

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 83%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NFAT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse NFAT5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1534 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NFAT5 antibody (ABIN183505)

Bire, Casteret, Piégu, Beauclair, Moiré, Arensbuger, Bigot: "Mariner Transposons Contain a Silencer: Possible Role of the Polycomb Repressive Complex 2." in: PLoS genetics, Vol. 12, Issue 3, pp. e1005902, (2016) (PubMed).

Target Details for NFAT5

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Alternative Name: NFAT5 (NFAT5 Products)

Background: Nfat5 contains 1 RHD (Rel-like) domain, and plays a role in the inducible expression of genes. Nfat5 regulates hypertonicity-induced cellular accumulation of osmolytes. Nfat5 might be capable of forming stable dimers with DNA elements
Alias Symbols: CAG-8, CAG80, OREBP, nfatz, NFATL1, TonEBP, AI225870, mKIAA0827, B130038B15Rik
Protein Size: 1534

Molecular Weight: 166 kDa

Gene ID: 54446

NCBI Accession: NM_018823

UniProt: Q9WV30

Pathways: RTK Signaling, WNT Signaling