CD68 antibody

Catalog No. ABIN1834923

Product Details anti-CD68 Antibody

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Macrosialin is a heavily glycosylated transmembrane protein of 87-115kD, which is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (LAMP) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeabilization. The antibody does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.

Purification: Protein G purified

Endotoxin Level: Low Endotoxin

Immunogen: Purified Concanavalin A acceptor glycoprotein from P815 cell line.

Type of Immunogen: Purified protein

Clone: FA-11

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68 (CD68 Products)

Background: Name/Gene ID: CD68

Synonyms: CD68, CD68 antigen, gp110, SCARD1, CD68 Molecule, LAMP4, Macrophage antigen CD68, Macrosialin

Gene ID: 968