PYCARD antibody (Middle Region)
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- Target See all PYCARD Antibodies
- PYCARD (PYD and CARD Domain Containing (PYCARD))
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Binding Specificity
- Middle Region
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PYCARD antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TVLRDMGLQE LAEQLQTTKE ESGAVAAAAS VPAQSTARTG HFVDQHRQAL
- Predicted Reactivity
- Mouse: 100%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against PYCARD. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of mouse PYCARD
- Top Product
- Discover our top product PYCARD Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 193 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PYCARD (PYD and CARD Domain Containing (PYCARD))
- Alternative Name
- PYCARD (PYCARD Products)
- Background
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Pycard is a cytosolic soluble protein that forms insoluble aggregates and enhances etoposide-induced apoptosis.
Alias Symbols: Asc, TNS1, masc, CARD5, TMS-1, 9130417A21Rik
Protein Size: 193 - Molecular Weight
- 21 kDa
- Gene ID
- 66824
- NCBI Accession
- NM_023258, NP_075747
- UniProt
- Q9EPB4
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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