KHDRBS1 antibody (N-Term)

Catalog No. ABIN183449

Product Details anti-KHDRBS1 Antibody

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHDRBS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MQRRDDPASR LTRSSGRSCS KDPSGAHPSV RLTPSRPSPL PHRPRGGGGG

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 86%, Human: 86%, Mouse: 100%, Pig: 92%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KHDRBS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse KHDRBS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 443 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KHDRBS1

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Alternative Name: KHDRBS1 (KHDRBS1 Products)

Background: Khdrbs1 functions as a transcriptional repressor and may link cellular signaling pathways with components of the transcriptional machinery. It shuttles between the nucleus and the cytoplasm in secondary spermatocytes, suggesting that it may promote translation of specific RNA targets during the meiotic divisions.
Alias Symbols: p62, p68, Sam68
Protein Interaction Partner: Rasa1, Yes1, Src, Lyn, Fyn, SH3KBP1, Cd40, Ripk1, TRAF2, Ncoa5, Rbm39, Gtf2e2, Khdrbs1, Grb2,
Protein Size: 443

Molecular Weight: 49 kDa

Gene ID: 20218

NCBI Accession: NM_011317, NP_035447

UniProt: Q60749

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy