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TFAM antibody (Middle Region)

TFAM Reactivity: Mouse, Rat, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN183430
  • Target See all TFAM Antibodies
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Binding Specificity
    • 15
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 54
    • 29
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Mouse, Rat, Rabbit
    Host
    • 81
    • 4
    Rabbit
    Clonality
    • 73
    • 12
    Polyclonal
    Conjugate
    • 41
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFAM antibody is un-conjugated
    Application
    • 65
    • 31
    • 22
    • 21
    • 18
    • 15
    • 14
    • 14
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    SESFQEAKDD SAQGKLKLVN EAWKNLSPEE KQAYIQLAKD DRIRYDNEMK
    Predicted Reactivity
    Mouse: 100%, Rabbit: 77%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against TFAM. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of mouse TFAM
    Top Product
    Discover our top product TFAM Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 243 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Alternative Name
    TFAM (TFAM Products)
    Background
    TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
    Alias Symbols: Hmgts, mtTFA, tsHMG, AI661103
    Protein Interaction Partner: C1QBP, SNCA,
    Protein Size: 243
    Molecular Weight
    27 kDa
    Gene ID
    21780
    NCBI Accession
    NM_009360, NP_033386
    UniProt
    P40630
    Pathways
    Chromatin Binding
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