P2RX6 antibody (N-Term)

Catalog No. ABIN183140

Product Details anti-P2RX6 Antibody

Target: P2RX6 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ERDLEPQFSI ITKLKGVSVT QIKELGNRLW DVADFVKPPQ GENVFFLVTN

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against P2RXL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human P2RXL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 431 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for P2RX6

Target: P2RX6 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))

Alternative Name: P2RXL1 (P2RX6 Products)

Synonyms: P2RXL1 antibody, P2X6 antibody, P2XM antibody, P2rxl1 antibody, P2x6 antibody, P2xm antibody, Rnap2x6 antibody, purinergic receptor P2X 6 antibody, purinergic receptor P2X, ligand-gated ion channel, 6 antibody, P2X purinoceptor 6 antibody, P2RX6 antibody, P2rx6 antibody, LOC100051842 antibody, LOC100588488 antibody

Background: P2RXL1 encodes a protein in the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. P2RXL1 is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells.
Alias Symbols: P2X6, P2XM, P2RXL1
Protein Interaction Partner: APP, CDH5,
Protein Size: 431

Molecular Weight: 47 kDa

Gene ID: 9127

NCBI Accession: NM_005446, NP_005437

UniProt: O15547