CLCNKB antibody (C-Term)
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- Target See all CLCNKB Antibodies
- CLCNKB (Chloride Channel Kb (CLCNKB))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CLCNKB antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ILAAGCPTEP VTLKLSPETS LHEAHNLFEL LNLHSLFVTS RGRAVGCVSW
- Predicted Reactivity
- Cow: 100%, Dog: 85%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against CLCNKB. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLCNKB
- Top Product
- Discover our top product CLCNKB Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 687 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CLCNKB (Chloride Channel Kb (CLCNKB))
- Alternative Name
- CLCNKB (CLCNKB Products)
- Background
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Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Alias Symbols: CLCKB, ClC-K2, ClC-Kb, hClC-Kb
Protein Interaction Partner: Dlg4,
Protein Size: 687 - Molecular Weight
- 76 kDa
- Gene ID
- 1188
- NCBI Accession
- NM_000085, NP_000076
- UniProt
- P51801
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