BMI1 antibody (C-Term)

Catalog No. ABIN182960

Product Details anti-BMI1 Antibody

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Horse, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMI1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TPVQSPHPQF PHISSTMNGT SNSPSGNHQS SFANRPRKSS VNGSSATSSG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against PCGF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PCGF4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMI1

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Alternative Name: PCGF4 (BMI1 Products)

Background: PCGF4 regulates telomerase expression in MECs and plays a role in the development of human breast cancer.
Alias Symbols: PCGF4, RNF51, FLVI2/BMI1
Protein Interaction Partner: RNF2, RING1, NDEL1, PHC2, UBC, TP53, HIST4H4, LENG8, PAXBP1, SFXN1, TIMM50, ZC3HAV1L, NME1, NHP2L1, NFX1, NDUFA4, NCL, NCBP1, MAGOH, CAPRIN1, KTN1, ILF3, ILF2, IK, HSPA1A, HIST1H2BB, HIST1H2BD, GTF3C1, GATA2, FUS, EWSR1, FBL, ERH, EP300, ELAVL1, ELAVL2, D
Protein Size: 326

Molecular Weight: 37 kDa

Gene ID: 648

NCBI Accession: NM_005180, NP_005171

UniProt: P35226

Pathways: Cell Division Cycle, Autophagy