CD4 antibody (FITC)

Catalog No. ABIN182100

Product Details anti-CD4 Antibody (FITC)

Target: CD4

Reactivity: Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises the CD4 cell surface antigen, a 50 kDa glycoprotein expressed by helper T lymphocytes.

Purification: Affinity Chromatography on Protein G

Immunogen: Rabbit thymocytes. Spleen cells from immunised mice were fused with cells of the mouse PAI myeloma cell line

Clone: KEN-4

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CD4

Target: CD4

Alternative Name: CD4 (CD4 Products)

Background: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gene ID: 100009152

UniProt: P46630

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events