F4/80 antibody

Catalog No. ABIN1819881

Product Details anti-F4/80 Antibody

Target: F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))

Reactivity: Human

Host: Hamster

Clonality: Monoclonal

Conjugate: This F4/80 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Recognizes human EMR1 (EGF-like module containing, mucin-like, hormone receptor-like 1). EMR1 is a seven-span transmembrane protein which is a member of the EGF-TM7 family of receptors. EMR1 is the human ortholog of murine F4/80 but unlike F4/80, the expression of EMR1 in humans is restricted to eosinophils and is not expressed on macrophage populations. The detailed structure and function of EMR1 is still unknown.

Purification: Protein G purified

Immunogen: Fibroblast cell line ARH102 expressing CD97-EMR1 (EGF1-6).

Type of Immunogen: Cells

Clone: A10

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for F4/80

Target: F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))

Alternative Name: ADGRE1 / EMR1 (EMR1 Products)

Background: Name/Gene ID: ADGRE1
Subfamily: Orphan-B
Family: GPCR

Synonyms: ADGRE1, EMR1 hormone receptor, F4/80, EGF-like module receptor 1, TM7LN3, EMR1

Gene ID: 2015

UniProt: Q14246