CD3 antibody

Catalog No. ABIN1819694

Product Details anti-CD3 Antibody

Target: CD3

Reactivity: Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes the canine CD3 cell surface antigen, expressed by thymocytes and mature T lymphocytes. CD3 is engaged in the surface expression of the T-cell antigen receptor (TCR) and the signal transduction pathway resulting from MHC ligand binding to the TCR. CD3 is made up of a number of invariant subchains of the immunoglobulin superfamily. Is a valuable flow cytometric and immunohistologic tool for canine lymphoma detection of T-cell origin.

Purification: Protein G purified

Immunogen: Affinity enriched TCR/CD3 membrane proteins isolated from thymocytes and the T cell line CLGL-90.

Type of Immunogen: Cells

Clone: CA17-2A12

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:25 - 1:50), IF, IHC, IHC-Fr, IHC-P, IP

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for CD3

Target: CD3

Alternative Name: CD3 (CD3 Products)

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway