CD3 antibody (FITC)

Catalog No. ABIN1819693

Product Details anti-CD3 Antibody (FITC)

Target: CD3

Reactivity: Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: Recognizes the canine CD3 cell surface antigen, expressed by thymocytes and mature T lymphocytes. CD3 is engaged in the surface expression of the T-cell antigen receptor (TCR) and the signal transduction pathway resulting from MHC ligand binding to the TCR. CD3 is made up of a number of invariant subchains of the immunoglobulin superfamily. Is a valuable flow cytometric and immunohistologic tool for canine lymphoma detection of T-cell origin.

Purification: Protein G purified

Immunogen: Affinity enriched TCR/CD3 membrane proteins isolated from thymocytes and the T cell line CLGL-90.

Type of Immunogen: Cells

Clone: CA17-2A12

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Protect from light.

Storage: 4 °C,-20 °C

Storage Comment: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Target Details for CD3

Target: CD3

Alternative Name: CD3 (CD3 Products)

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway