CCR4 antibody (AA 17-39)

Catalog No. ABIN1819413

Product Details anti-CCR4 Antibody

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Binding Specificity: AA 17-39

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Recognizes human CD194, otherwise known as CCR4 or C-C chemokine receptor type 4. CD194 is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by CD4+ Th2 (type 2 helper T) cells, which acts as a high affinity receptor for the chemokines MDC (macrophage-derived chemokine), MCP-1, MIP-1, RANTES and TARC.

Purification: Affinity purified

Immunogen: Synthetic peptide SNYYLYESIPKPCTKEGIKAFGE corresponding to amino acids 17-39 of human CD194. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey, Galago, Marmoset (100%), Gibbon, Panda (96%), Hamster, Dog, Horse, Pig (91%), Elephant, Rabbit (87%), Mouse, Cat (83%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (1:10000 - 1:30000), Flo (1:1), IHC, IHC-Fr, IHC-P (1:50 - 1:100), WB (1:100 - 1:500)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 0.1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4 (CCR4 Products)

Background: Name/Gene ID: CCR4
Subfamily: Chemokine
Family: GPCR

Synonyms: CCR4, C-C chemokine receptor type 4, CD194, CD194 antigen, C-C CKR-4, Chemr13, CKR-4, CC chemokine receptor 4, CC-CKR-4, CCR-4, HGCN:14099, C-c chemokine receptor 4, Chemokine (C-C) receptor 4, CKR4, CMKBR4, K5-5

Gene ID: 1233