C3 antibody
-
- Target See all C3 Antibodies
- C3 (Complement Component 3 (C3))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This C3 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Flow Cytometry (FACS)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Characteristics
- Synonyms: CPAMD1, Complement component 3, C3 and PZP-like alpha-2-macroglobulindomain-containing protein 1
- Purification
- Affinity Chromatography on Protein A
- Immunogen
- Purified C3d from Human plasma
- Clone
- 053A-1149-3-1-4 (1003)
- Isotype
- IgG1
- Top Product
- Discover our top product C3 Primary Antibody
-
anti-Complement Component 3 (C3) (AA 1000-1326) antibody
C3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1551-1663) antibodyC3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (fro), IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1644) antibodyC3 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) (C-Term) antibodyC3 Reactivity: Human WB, IP, IF, ICC, IHC (p), ISub Host: Rabbit Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 23-300) antibodyC3 Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 965-1303) antibodyC3 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1645) antibodyC3 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Mouse Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) antibodyC3 Reactivity: Mouse WB, IP, FACS, IF, IA Host: Rat Monoclonal 11H9 unconjugated
anti-Complement Component 3 (C3) (AA 966-1313) antibodyC3 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1644) antibodyC3 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
-
- Application Notes
-
ELISA. Western blot (1/5000). Flow Cytometry. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Borate buffered saline, pH 8.4, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
-
- Target
- C3 (Complement Component 3 (C3))
- Alternative Name
- Complement C3 (C3 Products)
- Background
- C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
- UniProt
- P01024
- Pathways
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
-
