LGR5 antibody (Cytoplasmic Domain)

Catalog No. ABIN1803976

Product Details anti-LGR5 Antibody

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Binding Specificity: Cytoplasmic Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGR5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human GPR49 / LGR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity purified

Immunogen: Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human GPR49 / LGR5. Percent identity with other species by BLAST analysis: Human (100%), Gibbon, Monkey (94%), Marmoset, Bat, Opossum (88%), Mouse, Rat, Hamster, Elephant, Panda (81%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC-P (5 - 10 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.

Expiry Date: 12 months

Target Details for LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Alternative Name: GPR49 / LGR5 (LGR5 Products)

Background: Name/Gene ID: LGR5
Subfamily: Orphan-A
Family: GPCR

Synonyms: LGR5, FEX, G-protein coupled receptor 49, G protein-coupled receptor 49, GPR67, GRP49, GPR49, HG38, G-protein coupled receptor 67

Gene ID: 8549

Pathways: WNT Signaling