CDX2 antibody (AA 176-303)
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- Target See all CDX2 Antibodies
- CDX2 (Caudal Type Homeobox 2 (CDX2))
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Binding Specificity
- AA 176-303
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CDX2 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- CDX2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CDX2 (AA: 176-303) expressed in E. Coli.
- Clone
- 3G9B9
- Isotype
- IgG1
- Top Product
- Discover our top product CDX2 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules." in: Tumour biology, Vol. 33, Issue 6, pp. 2185-8, (2012) (PubMed).
: "CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer." in: Cancer biology & therapy, Vol. 13, Issue 12, pp. 1152-7, (2012) (PubMed).
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CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules." in: Tumour biology, Vol. 33, Issue 6, pp. 2185-8, (2012) (PubMed).
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- Target
- CDX2 (Caudal Type Homeobox 2 (CDX2))
- Alternative Name
- CDX2 (CDX2 Products)
- Background
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Description: This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
Aliases: CDX3, CDX-3
- Molecular Weight
- 33.5kDa
- Gene ID
- 1045
- HGNC
- 1045
- UniProt
- Q99626
- Pathways
- Peptide Hormone Metabolism, Stem Cell Maintenance
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