beta Actin antibody (AA 1-375)

Catalog No. ABIN3020547

Product Details anti-beta Actin Antibody

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Binding Specificity: AA 1-375

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Actin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MDDDIAALVV DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAVL SLYASGRTTG IVMDSGDGVT HTVPIYEGYA LPHAILRLDL AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY ELPDGQVITI GNERFRCPEA LFQPSFLGME SCGIHETTFN SIMKCDVDIR KDLYANTVLS GGTTMYPGIA DRMQKEITAL APSTMKIKII APPERKYSVW IGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Loading control Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human beta-Actin (NP_001092.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-beta Actin antibody (ABIN3020547)

Zhu, Yuan, Liao, Li, Liu, Chen, Zhang, Cheng, Lu: "Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy." in: Cell death & disease, Vol. 9, Issue 8, pp. 837, (2018) (PubMed).

Chen, Zhang, Li, Feng, Zhang, Yao, Zhang, Wan: "Celastrol attenuates incision-induced inflammation and pain associated with inhibition of the NF-κB signalling pathway via SARM." in: Life sciences, Vol. 205, pp. 136-144, (2018) (PubMed).

Sun, Yu, Zhang, Zhu, Huang: "Respiratory syncytial virus infection up-regulates TLR7 expression by inducing oxidative stress via the Nrf2/ARE pathway in A549 cells." in: Archives of virology, Vol. 163, Issue 5, pp. 1209-1217, (2018) (PubMed).

Li, Kang, Yin, Li, Chen, Li, Zhang, Qiu: "Ginsenoside Rh2 inhibits human A172 glioma cell proliferation and induces cell cycle arrest status via modulating Akt signaling pathway." in: Molecular medicine reports, Vol. 17, Issue 2, pp. 3062-3068, (2018) (PubMed).

Ma, Gao, Wei, Jiang, Ding, He, Wei, Zhang: "The effects of celecoxib on the proliferation and ultrastructural changes of MDA-MB-231 breast cancer cells." in: Ultrastructural pathology, Vol. 42, Issue 3, pp. 289-294, (2018) (PubMed).

Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).

Ji, Xu, Huang, Li, Li, Zhang: "Molecular Characterization and Functional Analysis of a Putative Octopamine/Tyramine Receptor during the Developmental Stages of the Pacific Oyster, Crassostrea gigas." in: PLoS ONE, Vol. 11, Issue 12, pp. e0168574, (2017) (PubMed).

Wan, Schoenmaker, Jansen, Bian, de Vries, Everts: "Osteoblasts of calvaria induce higher numbers of osteoclasts than osteoblasts from long bone." in: Bone, Vol. 86, pp. 10-21, (2016) (PubMed).

Target Details for beta Actin

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Alternative Name: ACTB (ACTB Products)

Background: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.,ACTB,BRWS1,PS1TP5BP1,beta actin,actin,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Protein folding,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Immunology & Inflammation,ACTB

Molecular Weight: 41 kDa

Gene ID: 60

UniProt: P60709

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction