CEACAM1 antibody

Catalog No. ABIN1589887

Product Details anti-CEACAM1 Antibody

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Purpose: CEACAM-1 (D1-4) antibody

Specificity: Recombinant human sCEA-1 (D1-4)

Characteristics: Chromosomal location: 19q13.2
Produced from sera of rabbits immunized with highly pure recombinant human soluble CEACAM-1 (D1-4) (Carcinoembryonic antigen-related cell adhesion molecule-1, SwissProt: #P13688) as the immunizing antigen.

Purification: Anti-human soluble CEACAM-1 was purified by affinity chromatography with immobilized Protein A.

Immunogen: Recombinant human sCEA-1 (D1-4)

Isotype: IgG

Application Details

Application Notes: Western Blot: Use 2-5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: 4 °C,-20 °C

Storage Comment: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Expiry Date: 24 months

Target Details for CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Abstract: CEACAM1 Products

Background: CEACAM1, BGP, BGP1, BGPI, CD66a,Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.

Gene ID: 634

NCBI Accession: NM_001205344, NP_001192273

UniProt: P13688