FAS antibody

Catalog No. ABIN1502394

Product Details anti-FAS Antibody

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAS antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Specificity: This antibody reacts with CD95, a 40-45kD cell surface glycoprotein containing 8kD of N-glycosidic-linked polysaccharide and that is expressed by the CD45RAlow and CD45ROhigh subset of memory T cells.

Purification: Purified

Immunogen: Purified recombinant Fas antigen.

Type of Immunogen: Recombinant protein

Clone: B500

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:150 - 1:300), IHC (1:50 - 1:100)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 20 mM Tris-borate, 150 mM sodium chloride, dialyzed media RPMI 1640/D-MEM, Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, 0.05 % sodium azide,  pH 7.5

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: -20°C.

Target Details for FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Alternative Name: CD95 / FAS (FAS Products)

Background: Name/Gene ID: FAS
Family: TNF Receptor

Synonyms: FAS, ALPS1A, APO-1, APT1, Apo-1 antigen, APO-1 cell surface antigen, Apo11 antigen, Apoptosis antigen 1, CD95 antigen, Delta Fas/APO-1/CD95, Fas AMA, FAS1, Fasl receptors, FASLG receptor, FASTM, FAS 827dupA, Fasl receptor, TNFRSF6, CD95

Gene ID: 355

UniProt: P25445

Pathways: p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity