FAS antibody
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- Target See all FAS Antibodies
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This FAS antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Human/Rat CD95, Mr 45 kDa
- Characteristics
- Mouse Anti-Human CD95-LE/AF
- Endotoxin Level
- Low endotoxin
- Immunogen
- Human CD95 transfected L cells
- Clone
- DX3
- Isotype
- IgG2a
- Top Product
- Discover our top product FAS Primary Antibody
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anti-TNF Receptor Superfamily, Member 6 (FAS) antibody
FAS Reactivity: Human WB, FACS, ELISA, ICC Host: Mouse Monoclonal 4F8H6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 150-250) antibodyFAS Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibodyFAS Reactivity: Rat, Mouse WB, IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-172) antibodyFAS Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) antibodyFAS Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibodyFAS Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 185-211) antibodyFAS Reactivity: Human WB, IF Host: Rabbit Polyclonal RB21902 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 2G3 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 5B4 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibodyFAS Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 1B6 unconjugated
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- Application Notes
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- Applications: FC - Quality tested , IHC-PS - Reported in literature , ELISA - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC and SPRD conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Comment
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in vivo induction of apoptosis
- Sample Volume
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- Preservative
- Azide free
- Handling Advice
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Storage
- -20 °C
- Storage Comment
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- Target
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Alternative Name
- CD95 (FAS Products)
- Background
- CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells, indicating that these monoclonal antibodies recognize a functional epitope of CD95.
- Pathways
- p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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