Endoglin antibody

Catalog No. ABIN135375

Product Details anti-Endoglin Antibody

Target: Endoglin (ENG)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Mouse CD105, Mr 90 kDa

Characteristics: Rat Anti-Mouse CD105-UNLB

Purification: Purified

Immunogen: Inflamed mouse skin

Clone: MJ7-18

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , WB - Reported in literature , Sep - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells PACBLU conjugate 1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105 (ENG Products)

Background: CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit > 70 % sequence homology in their cytoplasmic domains with type III transforming growth factor (TGF) receptor. CD105 has been shown to be one of several receptors for the various isoforms of TGF, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response.