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CD19 antibody

CD19 Reactivity: Mouse FACS Host: Mouse Monoclonal MB19-1 unconjugated
Catalog No. ABIN135153
  • Target See all CD19 Antibodies
    CD19 (CD19 Molecule (CD19))
    Reactivity
    • 275
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    • 39
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    Mouse
    Host
    • 170
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    • 48
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    Mouse
    Clonality
    • 228
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    Monoclonal
    Conjugate
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    This CD19 antibody is un-conjugated
    Application
    • 258
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    Flow Cytometry (FACS)
    Specificity
    Mouse CD19, Mr 95 kDa
    Characteristics
    Mouse Anti-Mouse CD19-UNLB
    Purification
    Purified
    Immunogen
    CD19+ mouse pre-B cell line 300.19
    Clone
    MB19-1
    Isotype
    IgA
    Top Product
    Discover our top product CD19 Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IP - Reported in literature , Activ - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells APC/CY5.5 and APC/CY7 conjugates 0.3 g/106 cells PE, APC, SPRD, and PE/CY5.5 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Preservative
    Without preservative
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    CD19 (CD19 Molecule (CD19))
    Alternative Name
    CD19 (CD19 Products)
    Background
    CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e., B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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